Notch Signaling and PD-1/PD-L1 Interaction in Hepatocellular Carcinoma: Potentialities of Combined Therapies

Immunotherapy has shown significant improvement in the survival of patients with hepatocellular carcinoma (HCC) compared to TKIs as first-line treatment. Unfortunately, approximately 30% of HCC exhibits intrinsic resistance to ICIs, making new therapeutic combinations urgently needed. The dysregulat...

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Principais autores:	Annapaola Montagner, Andrea Arleo, Fabrizia Suzzi, Antonino B. D’Assoro, Fabio Piscaglia, Laura Gramantieri, Catia Giovannini
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2024-12-01
Series:	Biomolecules
Assuntos:	Notch PD-1 PD-L1 hepatocellular carcinoma (HCC) immunotherapy combination therapy
Acceso en liña:	https://www.mdpi.com/2218-273X/14/12/1581
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