A Novel LC-MS/MS Method for the Measurement of Elexacaftor, Tezacaftor and Ivacaftor in Plasma, Dried Plasma Spot (DPS) and Whole Blood in Volumetric Absorptive Microsampling (VAMS) Devices

<b>Background:</b> The combination of ivacaftor, tezacaftor and elexacaftor (ETI) is approved for patients with cystic fibrosis (CF) aged two years and older and at least one F508del mutation in the CFTR gene. Variability in ETI treatment response has been repeatedly reported, and its reasons are un...

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Bibliografiske detaljer

Principais autores:	Federica Pigliasco, Alessia Cafaro, Sebastiano Barco, Federico Cresta, Rosaria Casciaro, Nicoletta Pedemonte, Francesca Mattioli, Carlo Castellani, Giuliana Cangemi
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2025-02-01
Serier:	Pharmaceutics
Fag:	CFTR modulators cystic fibrosis liquid chromatograph–tandem mass spectrometry microsampling pediatric pharmacology
Online adgang:	https://www.mdpi.com/1999-4923/17/2/200
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