Novel HDAC/Tubulin Dual Inhibitor: Design, Synthesis and Docking Studies of α-Phthalimido-Chalcone Hybrids as Potential Anticancer Agents with Apoptosis-Inducing Activity

Ahmed A E Mourad,1 Mai A E Mourad,2 Peter G Jones3 1Pharmacology and Toxicology Department, Faculty of Pharmacy, Port-Said University, Port-Said, Egypt; 2Medicinal Chemistry Department, Faculty of Pharmacy, Port-Said University, Port-Said, Egypt; 3Institute of Inorganic and Analytical Chemistry, Bra...

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Principais autores:	Mourad AAE, Mourad MAE, Jones PG
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Dove Medical Press 2020-08-01
coleção:	Drug Design, Development and Therapy
Assuntos:	chalcones -phthalimido- anticancer cell cycle histone deacetylase inhibitor tubulin polymerase inhibitor
Acesso em linha:	https://www.dovepress.com/novel-hdactubulin-dual-inhibitor-design-synthesis-and-docking-studies--peer-reviewed-article-DDDT
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