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Glycation Interferes with the Expression of Sialyltransferases and Leads to Increased Polysialylation in Glioblastoma Cells

Glioblastoma (GBM) is a highly aggressive brain tumor that often utilizes aerobic glycolysis for energy production (Warburg effect), resulting in increased methylglyoxal (MGO) production. MGO, a reactive dicarbonyl compound, causes protein alterations and cellular dysfunction via glycation. In this...

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Egile Nagusiak: Paola Schildhauer, Philipp Selke, Martin S. Staege, Anja Harder, Christian Scheller, Christian Strauss, Rüdiger Horstkorte, Maximilian Scheer, Sandra Leisz
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI AG 2023-12-01
Saila:Cells
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Sarrera elektronikoa:https://www.mdpi.com/2073-4409/12/23/2758
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