Subcellular clearance and accumulation of Huntington disease protein: A mini-review
Huntington’s disease (HD) is an autosomal dominant, progressive neurodegenerative disease caused by an expanded polyglutamine (polyQ) tract in the N-terminal region of mutant huntingtin (mHtt). As a result, mHtt forms aggregates that are abundant in the nuclei and processes of neuronal cells. Althou...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Frontiers Media S.A.
2016-04-01
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| Σειρά: | Frontiers in Molecular Neuroscience |
| Θέματα: | |
| Διαθέσιμο Online: | http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00027/full |
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