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Elevated expression of immune checkpoints and pro-inflammatory cytokines as potential biomarkers in pediatric Vulvar Lichen Sclerosus

Abstract Vulvar Lichen Sclerosus (VLS) is a chronic inflammatory dermatosis of unknown etiology affecting the external genitalia. In pediatric patients, it can lead to significant discomfort and progressive structural changes in tissues. In recent years, there has been increasing interest in the par...

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Principais autores: Ewelina Grywalska, Paulina Mertowska, Sebastian Mertowski, Monika Zaborek-Łyczba, Jakub Łyczba, Ewa Woźniakowska, Karolina Rasoul-Pelińska, Kamila Ćwik, Anna Torres
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2026-02-01
Serier:Scientific Reports
Fag:
Lichen Sclerosus et Atrophicus
Child
Cytokines
Immune system
Online adgang:https://doi.org/10.1038/s41598-025-33630-2
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