Using deep neural networks and LASSO regression to predict miRNA expression changes based on mRNA data

IntroductionSince the rise of molecular high-throughput technologies, many diseases are now studied on multiple omics layers in parallel. Understanding the interplay between microRNAs (miRNA) and their target mRNAs is important to understand the molecular level of diseases. While much public data fr...

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Principais autores:	Franz Leonard Böge, Helena U. Zacharias, Stefanie C. Becker, Klaus Jung
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2025-07-01
סדרה:	Frontiers in Bioinformatics
נושאים:	microRNA artificial neural networks LASSO regularization West Nile virus human immunodeficiency virus multi-omics
גישה מקוונת:	https://www.frontiersin.org/articles/10.3389/fbinf.2025.1566162/full
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