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CRISPR as a Tool to Uncover Gene Function in Polycystic Ovary Syndrome: A Literature Review of Experimental Models Targeting Ovarian and Metabolic Genes

Polycystic ovary syndrome (PCOS) is a complex disorder characterized by reproductive abnormalities such as hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphology, and is frequently accompanied by metabolic disturbances such as insulin resistance, obesity and dyslipidemia. Genome-...

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Principais autores: Shahd Bucheeri, Yasmine Alcibahy, Yara Bucheeri, Sarah Bucheeri, Abrar Alhermi, Alexandra E. Butler
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-11-01
Serier:Cells
Fag:
polycystic ovary syndrome (PCOS)
CRISPR/Cas9
gene editing
functional genomics
Online adgang:https://www.mdpi.com/2073-4409/14/22/1769
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