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The role of cell-mediated immunity against influenza and its implications for vaccine evaluation

Influenza vaccines remain the most effective tools to prevent flu and its complications. Trivalent or quadrivalent inactivated influenza vaccines primarily elicit antibodies towards haemagglutinin and neuraminidase. These vaccines fail to induce high protective efficacy, in particular in older adult...

Celý popis

Uloženo v:
Hlavní autoři: Yorick Janssens, Jasper Joye, Gwenn Waerlop, Frédéric Clement, Geert Leroux-Roels, Isabel Leroux-Roels
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2022-08-01
Edice:Frontiers in Immunology
Témata:
influenza
cellular immunity
vaccine
clinical trial
correlate of protection
T-cell
On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2022.959379/full
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