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Polyanionic candidate microbicides accelerate the formation of semen-derived amyloid fibrils to enhance HIV-1 infection.

Polyanionic candidate microbicides, including cellulose sulfate, carrageenan, PRO 2000, were proven ineffective in preventing HIV-1 transmission and even cellulose sulfate showed increased risk of HIV acquisition in the Phase III efficacy trials. Semen plays critical roles in HIV-1 sexual transmissi...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Suiyi Tan, Lu Lu, Lin Li, Jixiang Liu, Yelena Oksov, Hong Lu, Shibo Jiang, Shuwen Liu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science (PLoS) 2013-01-01
Sarja:PLoS ONE
Linkit:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0059777&type=printable
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