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Evaluation of (-)-Fenchone antimicrobial activity against oral Candida albicans and toxicological parameters: an in silico, in vitro and ex vivo study

Abstract Candida albicans is the primary species causing oral candidiasis. Its increasing drug resistance drives the search for more effective antifungal agents. Therefore, we assessed toxicological parameters and the antimicrobial activity and mechanisms of action of the monoterpene (-)-fenchone ag...

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Autori principali: ANDRÉ A. DOS SANTOS, ABRAHÃO A. DE OLIVEIRA-FILHO, BRÁULIO A. TEIXEIRA, JOSÉ LUCAS F.M. GALVÃO, MARIA ALICE A. DE MEDEIROS, MILLENA S. ALVES, DAVID HENRIQUE X. BARBOSA, RODRIGO P. MAFRA, ULRICH VASCONCELOS, EDELTRUDES O. LIMA
Natura: Artigo
Lingua:Inglês
Pubblicazione: Academia Brasileira de Ciências 2024-11-01
Serie:Anais da Academia Brasileira de Ciências
Soggetti:
oral candidiasis
monoterpenes
antifungal activity
antibiofilm activity
antifungal agents
L-fenchone
Accesso online:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652024000600905&lng=en&tlng=en
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