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Improving the Predictive Value of Prion Inactivation Validation Methods to Minimize the Risks of Iatrogenic Transmission With Medical Instruments

Prions are pathogenic infectious agents responsible for fatal, incurable neurodegenerative diseases in animals and humans. Prions are composed exclusively of an aggregated and misfolded form (PrPSc) of the cellular prion protein (PrPC). During the propagation of the disease, PrPSc recruits and misfo...

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Gardado en:
Principais autores: Mohammed Moudjou, Johan Castille, Bruno Passet, Laetitia Herzog, Fabienne Reine, Jean-Luc Vilotte, Human Rezaei, Vincent Béringue, Angélique Igel-Egalon
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Bioengineering and Biotechnology
Assuntos:
prion
sporadic CJD
amplification
PMCA
surface
decontamination
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fbioe.2020.591024/full
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