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Perilipin overexpression in mice protects against diet-induced obesity

Perilipin A is the most abundant phosphoprotein on adipocyte lipid droplets and is essential for lipid storage and lipolysis. Perilipin null mice exhibit diminished adipose tissue, elevated basal lipolysis, reduced catecholamine-stimulated lipolysis, and increased insulin resistance. To understand t...

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Principais autores: Hideaki Miyoshi, Sandra C. Souza, Mikiko Endo, Takashi Sawada, James W. Perfield, II, Chikara Shimizu, Zlatina Stancheva, So Nagai, Katherine J. Strissel, Narihito Yoshioka, Martin S. Obin, Takao Koike, Andrew S. Greenberg
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2010-05-01
Colecção:Journal of Lipid Research
Assuntos:
adipocyte
lipolysis
transgenic mice
lipid oxidation
glucose tolerance
insulin resistance
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0022227520410521
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