Suppressor Mutations in LptF Bypass Essentiality of LptC by Forming a Six-Protein Transenvelope Bridge That Efficiently Transports Lipopolysaccharide

ABSTRACT Lipopolysaccharide (LPS) is an essential component of the outer membrane (OM) of many Gram-negative bacteria, providing a barrier against the entry of toxic molecules. In Escherichia coli, LPS is exported to the cell surface by seven essential proteins (LptA-G) that form a transenvelope com...

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Autors principals:	Federica A. Falchi, Rebecca J. Taylor, Sebastian J. Rowe, Elisabete C. C. M. Moura, Tiago Baeta, Cedric Laguri, Jean-Pierre Simorre, Daniel E. Kahne, Alessandra Polissi, Paola Sperandeo
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology 2023-02-01
Col·lecció:	mBio
Matèries:	ABC transporter ATPase lipopolysaccharide transport cell envelope outer membrane biogenesis proteoliposomes
Accés en línia:	https://journals.asm.org/doi/10.1128/mbio.02202-22
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