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In situ proteolysis to generate crystals for structure determination: an update.

For every 100 purified proteins that enter crystallization trials, an average of 30 form crystals, and among these only 13-15 crystallize in a form that enables structure determination. In 2007, Dong et al reported that the addition of trace amounts of protease to crystallization trials--in situ pro...

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Detalles Bibliográficos
Principais autores: Amy Wernimont, Aled Edwards
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC2661377?pdf=render
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