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Inferior Olive HCN1 Channels Coordinate Synaptic Integration and Complex Spike Timing

Summary: Cerebellar climbing-fiber-mediated complex spikes originate from neurons in the inferior olive (IO), are critical for motor coordination, and are central to theories of cerebellar learning. Hyperpolarization-activated cyclic-nucleotide-gated (HCN) channels expressed by IO neurons have been...

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Principais autores: Derek L.F. Garden, Marlies Oostland, Marta Jelitai, Arianna Rinaldi, Ian Duguid, Matthew F. Nolan
פורמט: Artigo
שפה:Inglês
יצא לאור: Elsevier 2018-02-01
סדרה:Cell Reports
נושאים:
excitability
synaptic integration
oscillation
gap junction
inferior olive
cerebellum
גישה מקוונת:http://www.sciencedirect.com/science/article/pii/S2211124718301189
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