Haploidentical transplantation combined with mesenchymal stem cells co-infusion improves survival in severe aplastic anemia: a single-center retrospective study

BackgroundHaploidentical hematopoietic stem cell transplantation (HID-HSCT) serves as an alternative treatment for severe aplastic anemia (SAA) patients lacking a suitable HLA-identical sibling donor. Compared to HLA-matched HSCT, HID-HSCT has higher rates of graft failure (GF) and graft-versus-host...

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Auteurs principaux:	Zhengwei Tan, Miaoya Le, Ningning Zhu, Jingjing Liu, Yuechao Zhao, Huijin Hu, Qinghong Yu, Yu Zhang, Liqiang Wu, Tonglin Hu, Dijiong Wu, Baodong Ye, Wenbin Liu
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2025-11-01
Collection:	Frontiers in Medicine
Sujets:	aplastic anemia haploidentical hematopoietic stem cell transplantation mesenchymal stem cells graft-versus-host disease overall survival
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fmed.2025.1711958/full
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