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Evaluating the oxysterol combination of 22(S)-hydroxycholesterol and 20(S)-hydroxycholesterol in periodontal regeneration using periodontal ligament stem cells and alveolar bone healing models

Abstract Background Oxysterols, oxygenated by-products of cholesterol biosynthesis, play roles in various physiological and pathological systems. However, the effects of oxysterols on periodontal regeneration are unknown. This study investigated the effects of the specific oxysterol combination of 2...

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Principais autores: Jin-Sun Lee, EunJi Kim, Seonggu Han, Kyung Lhi Kang, Jung Sun Heo
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-12-01
coleção:Stem Cell Research & Therapy
Assuntos:
Oxysterol
Periodontal ligament stem cells
Osteogenic differentiation
Alveolar bone defect
Bone regeneration
Acesso em linha:http://link.springer.com/article/10.1186/s13287-017-0725-9
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