Mast cells-intestinal cancer cells crosstalk is mediated by TNF-alpha and sustained by the IL-33/ST2 axis

Abstract It is common knowledge that mast cells (MCs) exert different roles in the gastrointestinal tract, from the maintenance of homeostasis to the onset and propagation of different gut diseases such as food allergies, infections, inflammation, and cancer. However, the mechanisms through which MC...

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主要な著者:	Chiara Dal Secco, Silvia Tonon, Caterina Trevisan, Eleonora Martinis, Viviana Valeri, Marta Codrich, Gianluca Tell, Barbara Frossi, Carlo E. M. Pucillo
フォーマット:	Artigo
言語:	Inglês
出版事項:	Springer 2025-05-01
シリーズ:	Cancer Immunology, Immunotherapy
主題:	Mast cells Organoids Co-cultures TNF-α IL-33 Intestinal differentiation and architecture
オンライン･アクセス:	https://doi.org/10.1007/s00262-025-04054-8
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