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The validity of immunohistochemistry in detecting microsatellite instability in pediatric solid neoplasms

Background: The DNA mismatch repair (MMR) is the biological pathway that plays a key role in maintaining genomic stability during DNA replication and recombination. The value of MMR pathway is under investigation in pediatrics' solid tumors. Aims: In this research work, we investigated the proteins...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Khaldoon Aljerian, Waleed AlRajban, Tariq Aljohani, Ali Alshehri, Omar Alsherif, Musa Alharbi, Ibraheem Abosoudah, Wasil Jastaniah, Saad Al Daama, Abdulrahman AlSultan, Nahaa Eid Alsubaie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wolters Kluwer Medknow Publications 2024-01-01
Schriftenreihe:Journal of Nature and Science of Medicine
Schlagworte:
dna mismatch repair
immunohistochemistry
microsatellite instability
pms2
Online-Zugang:http://www.jnsmonline.org/article.asp?issn=2589-627X;year=2024;volume=7;issue=2;spage=122;epage=128;aulast=Aljerian
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