CTH/MPST double ablation results in enhanced vasorelaxation and reduced blood pressure via upregulation of the eNOS/sGC pathway

Hydrogen sulfide (H2S), a gasotransmitter with protective effects in the cardiovascular system, is endogenously generated by three main enzymatic pathways: cystathionine gamma lyase (CTH), cystathionine beta synthase (CBS) and 3-mercaptopyruvate sulfurtransferase (MPST) enzymes. CTH and MPST are the...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Antonia Katsouda, Maria Markou, Paraskevas Zampas, Aimilia Varela, Constantinos H. Davos, Valentina Vellecco, Giuseppe Cirino, Mariarosaria Bucci, Andreas Papapetropoulos
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2023-02-01
Serie:	Frontiers in Pharmacology
Soggetti:	cystathine γ-lyase mercaptopyruvate sulfurtransferase blood pressure vasorelaxation nitric oxide synthase hydrogen sulfide
Accesso online:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1090654/full
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!