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Comparative transcriptomics coupled to developmental grading via transgenic zebrafish reporter strains identifies conserved features in neutrophil maturation

Abstract Neutrophils are evolutionarily conserved innate immune cells playing pivotal roles in host defense. Zebrafish models have contributed substantially to our understanding of neutrophil functions but similarities to human neutrophil maturation have not been systematically characterized, which...

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Bibliografiske detaljer
Principais autores: Stefanie Kirchberger, Mohamed R. Shoeb, Daria Lazic, Andrea Wenninger-Weinzierl, Kristin Fischer, Lisa E. Shaw, Filomena Nogueira, Fikret Rifatbegovic, Eva Bozsaky, Ruth Ladenstein, Bernd Bodenmiller, Thomas Lion, David Traver, Matthias Farlik, Christian Schöfer, Sabine Taschner-Mandl, Florian Halbritter, Martin Distel
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2024-02-01
Serier:Nature Communications
Online adgang:https://doi.org/10.1038/s41467-024-45802-1
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