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The Development and Validation of a Novel Nanobody-Based Competitive ELISA for the Detection of Foot and Mouth Disease 3ABC Antibodies in Cattle

Effective management of foot and mouth disease (FMD) requires diagnostic tests to distinguish between infected and vaccinated animals (DIVA). To address this need, several enzyme-linked immunosorbent assay (ELISA) platforms have been developed, however, these tests vary in their sensitivity and spec...

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Huvudupphov: Sigal Gelkop, Ariel Sobarzo, Polina Brangel, Cécile Vincke, Ema Romão, Shlomit Fedida-Metula, Nick Strom, Irene Ataliba, Frank Norbet Mwiine, Sylvester Ochwo, Lauro Velazquez-Salinas, Rachel A. McKendry, Serge Muyldermans, Julius Julian Lutwama, Elizabeth Rieder, Victoria Yavelsky, Leslie Lobel
Materialtyp: Artigo
Språk:Inglês
Utgiven: Frontiers Media S.A. 2018-10-01
Serie:Frontiers in Veterinary Science
Ämnen:
foot and mouth disease
non-structural proteins
nanobodies
antibodies
ELISA
Länkar:https://www.frontiersin.org/article/10.3389/fvets.2018.00250/full
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