Diacylglycerol kinase-ε is required for the formation of GPI-anchored CD14 and the LPS-induced proinflammatory responses of macrophages

Abstract Background Diacylglycerol kinase-ε (DGKε) is a unique member of the DGK family with strict specificity toward SAG, stearic/palmitic and arachidonic fatty acid-containing DAG, which produces phosphatidic acid used for the synthesis of phosphatidylinositol (PI). PI and its derivatives orchest...

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Κύριοι συγγραφείς:	Aneta Hromada-Judycka, Gabriela Traczyk, Ichrak Ben Amor, Anna Ciesielska, Aniela Mąkosa, Daniel Varon Silva, Katarzyna Kwiatkowska
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2026-04-01
Σειρά:	Cell Communication and Signaling
Θέματα:	Diacylglycerol kinase CD14 GPI anchor LPS TLR signaling Pro-inflammatory signaling
Διαθέσιμο Online:	https://doi.org/10.1186/s12964-026-02884-2
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