Synthesis and Biological Evaluation of Novel Allobetulon/Allobetulin–Nucleoside Conjugates as AntitumorAgents

Allobetulin is structurally similar tobetulinic acid, inducing the apoptosis of cancer cells with low toxicity. However, both of them exhibited weak antiproliferation against several tumor cell lines. Therefore, the new series of allobetulon/allobetulin–nucleoside conjugates <b>9a</b>–<b>10i</b> wer...

Descripción completa

Detalles Bibliográficos

Autores principales:	Yanli Wang, Xiaowan Huang, Xiao Zhang, Jingchen Wang, Keyan Li, Guotao Liu, Kexin Lu, Xiang Zhang, Chengping Xie, Teresa Zheng, Yung-Yi Cheng, Qiang Wang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2022-07-01
Colección:	Molecules
Materias:	pentacyclic triterpene allobetulin conjugates antitumor activity apoptosis nucleosides
Acceso en línea:	https://www.mdpi.com/1420-3049/27/15/4738
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!