The plasticity of primary microglia and their multifaceted effects on endogenous neural stem cells in vitro and in vivo

Abstract Background Microglia—the resident immune cells of the brain—are activated after brain lesions, e.g., cerebral ischemia, and polarize towards a classic “M1” pro-inflammatory or an alternative “M2” anti-inflammatory phenotype following characteristic temporo-spatial patterns, contributing eit...

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Detalhes bibliográficos

Principais autores:	Sabine Ulrike Vay, Lea Jessica Flitsch, Monika Rabenstein, Rebecca Rogall, Stefan Blaschke, Judith Kleinhaus, Noémie Reinert, Annika Bach, Gereon Rudolf Fink, Michael Schroeter, Maria Adele Rueger
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2018-08-01
coleção:	Journal of Neuroinflammation
Assuntos:	Neuroinflammation Neuroprotection Stem cell-mediated regeneration M1 microglia M2 microglia Hybrid microglia
Acesso em linha:	http://link.springer.com/article/10.1186/s12974-018-1261-y
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