Development of a live cell assay for real-time monitoring the interactions between the Hippo pathway components 14-3-3 and TAZ

The Hippo pathway plays an important role in organ size control and tissue homeostasis. Dysregulation is involved in many pathologies, including cancer, which has attracted interest in targeting the Hippo pathway. Since the upstream components are bona fide tumor suppressors, it is feasible to targe...

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Detalhes bibliográficos

Principais autores:	Blaž Andlovic, Alexander Wolf, Malgorzata Hiltmann, Bert M. Klebl, Jan Eickhoff, Christian Ottmann
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-12-01
Colecção:	SLAS Discovery
Assuntos:	Cell-based assay Protein-protein interactions Split-luciferase complementation Hippo pathway Compound screening
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2472555224000534
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