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Regulation of the maturation of human monocytes into immunosuppressive macrophages

Abstract: Human monocytes differentiate into either proinflammatory or immunosuppressive macrophages in response to distinct stimuli. Results show that the Toll-like receptor 2/1 agonist PAM3 replicates the ability of macrophage colony-stimulating factor (M-CSF) to induce the preferential generation...

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Bibliographic Details
Main Authors: Defne Bayik, Debra Tross, Lydia A. Haile, Daniela Verthelyi, Dennis M. Klinman
Format: Artigo
Language:Inglês
Published: Elsevier 2017-12-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952920300835
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