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Macrophages and microglia in glioblastoma: heterogeneity, plasticity, and therapy

Glioblastoma (GBM) is the most aggressive tumor in the central nervous system and contains a highly immunosuppressive tumor microenvironment (TME). Tumor-associated macrophages and microglia (TAMs) are a dominant population of immune cells in the GBM TME that contribute to most GBM hallmarks, includ...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Fatima Khan, Lizhi Pang, Madeline Dunterman, Maciej S. Lesniak, Amy B. Heimberger, Peiwen Chen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2023-01-01
Schriftenreihe:The Journal of Clinical Investigation
Online-Zugang:https://doi.org/10.1172/JCI163446
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