Single-Cell DNA Methylome Sequencing and Bioinformatic Inference of Epigenomic Cell-State Dynamics

Methods for single-cell genome and transcriptome sequencing have contributed to our understanding of cellular heterogeneity, whereas methods for single-cell epigenomics are much less established. Here, we describe a whole-genome bisulfite sequencing (WGBS) assay that enables DNA methylation mapping...

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Autors principals:	Matthias Farlik, Nathan C. Sheffield, Angelo Nuzzo, Paul Datlinger, Andreas Schönegger, Johanna Klughammer, Christoph Bock
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2015-03-01
Col·lecció:	Cell Reports
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2211124715001096
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