Viral miRNA adaptor differentially recruits miRNAs to target mRNAs through alternative base-pairing

HSUR2 is a viral non-coding RNA (ncRNA) that functions as a microRNA (miRNA) adaptor. HSUR2 inhibits apoptosis in infected cells by recruiting host miRNAs miR-142–3p and miR-16 to mRNAs encoding apoptotic factors. HSUR2’s target recognition mechanism is not understood. It is also unknown why HSUR2 u...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Carlos Gorbea, Tim Mosbruger, David A Nix, Demián Cazalla
Formato:	Artigo
Idioma:	Inglês
Publicado em:	eLife Sciences Publications Ltd 2019-09-01
Colecção:	eLife
Assuntos:	marmoset Herpesvirus saimiri RNA-RNA interaction miRNA mRNA regulation
Acesso em linha:	https://elifesciences.org/articles/50530
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!