Circ VRK1/microRNA-17/PTEN axis modulates the angiogenesis of human brain microvascular endothelial cells to affect injury induced by oxygen-glucose deprivation/reperfusion

Abstract Background Circular RNAs (circRNAs) can act as microRNA (miRNA) sponges, thus regulating gene expression. The role of circRNAs in the process of oxygen-glucose deprivation/reoxygenation (OGD/R) is unclear. Here, we explored the mechanism underlying Circ VRK1 in human brain microvascular end...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Lei Yang, Hong Du, Xuejing Zhang, Bulang Gao, Dongliang Zhang, Zongrong Qiao, Xianhui Su, Tong Bao, Siqin Han
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	BMC 2023-01-01
Sarja:	BMC Neuroscience
Aiheet:	Circ VRK1 microRNA-17 PTEN PI3K/AKT pathway Oxygen-glucose deprivation/reoxygenation
Linkit:	https://doi.org/10.1186/s12868-023-00774-8
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