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Simulations of Asymmetric Membranes Illustrate Cooperative Leaflet Coupling and Lipid Adaptability

Biological membranes are composed of lipid bilayers that are often asymmetric with regards to the lipid composition and/or aqueous solvent they separate. Studying lipid asymmetry both experimentally and computationally is challenging. Molecular dynamics simulations of lipid bilayers with asymmetry a...

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Principais autores: Madison Blumer, Sophia Harris, Mengzhe Li, Luis Martinez, Michael Untereiner, Peter N. Saeta, Timothy S. Carpenter, Helgi I. Ingólfsson, W. F. Drew Bennett
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020-07-01
Serier:Frontiers in Cell and Developmental Biology
Fag:
lipid membrane
membrane asymmetry
molecular dynamic simulations
cholesterol
multiscale modeling
Online adgang:https://www.frontiersin.org/article/10.3389/fcell.2020.00575/full
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