Novel Pyrrole Derivatives as Multi-Target Agents for the Treatment of Alzheimer’s Disease: Microwave-Assisted Synthesis, In Silico Studies and Biological Evaluation

Considering the complex pathogenesis of Alzheimer’s disease (AD), the multi-target ligand strategy is expected to provide superior effects for the treatment of the neurological disease compared to the classic single target strategy. Thus, one novel pyrrole-based hydrazide (<b>vh0</b>) and four corre...

पूर्ण विवरण

ग्रंथसूची विवरण

मुख्य लेखकों:	Emilio Mateev, Valentin Karatchobanov, Marjano Dedja, Konstantinos Diamantakos, Alexandrina Mateeva, Muhammed Tilahun Muhammed, Ali Irfan, Magdalena Kondeva-Burdina, Iva Valkova, Maya Georgieva, Alexander Zlatkov
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	MDPI AG 2024-09-01
श्रृंखला:	Pharmaceuticals
विषय:	microwave-assisted synthesis pyrrole hydrazide–hydrazones antioxidants oxidative stress molecular docking
ऑनलाइन पहुंच:	https://www.mdpi.com/1424-8247/17/9/1171
टैग:	टैग जोड़ें कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!