Increased myocellular lipid and IGFBP‐3 expression in a pre‐clinical model of pancreatic cancer‐related skeletal muscle wasting

Abstract Background Skeletal muscle wasting (SMW) in cancer patients is associated with increased morbidity, mortality, treatment intolerance and discontinuation, and poor quality of life. This is particularly true for patients with pancreatic ductal adenocarcinoma (PDAC), as over 85% experience SMW...

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Autori principali:	Calvin L. Cole, John F. Bachman, Jian Ye, Joseph Murphy, Scott A. Gerber, Christopher A. Beck, Brendan F. Boyce, Gowrishankar Muthukrishnan, Joe V. Chakkalakal, Edward M. Schwarz, David Linehan
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2021-06-01
Serie:	Journal of Cachexia, Sarcopenia and Muscle
Soggetti:	Myocellular lipid Murine model Pancreatic cancer Skeletal muscle wasting
Accesso online:	https://doi.org/10.1002/jcsm.12699
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