ATM release at resected double-strand breaks provides heterochromatin reconstitution to facilitate homologous recombination.
Non-homologous end-joining (NHEJ) and homologous recombination (HR) represent the two main pathways for repairing DNA double-strand breaks (DSBs). During the G2 phase of the mammalian cell cycle, both processes can operate and chromatin structure is one important factor which determines DSB repair p...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science (PLoS)
2013-01-01
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| Series: | PLoS Genetics |
| Acceso en liña: | http://europepmc.org/articles/PMC3731223?pdf=render |
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