Allergen-Specific IgA Antibodies Block IgE-Mediated Activation of Mast Cells and Basophils

Mast cells and basophils have long been implicated in the pathogenesis of IgE-mediated hypersensitivity reactions. They express the high-affinity IgE receptor, FcϵRI, on their surface. Antigen-induced crosslinking of IgE antibodies bound to that receptor triggers a signaling cascade that results in...

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Bibliografski detalji

Glavni autori:	Yasmeen S. El Ansari, Cynthia Kanagaratham, Oliver T. Burton, Jenna V. Santos, Brianna-Marie A. Hollister, Owen L. Lewis, Harald Renz, Hans C. Oettgen
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2022-07-01
Serija:	Frontiers in Immunology
Teme:	basophils basophil activation test allergy IgE IgA oral immunotherapy (OIT)
Online pristup:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.881655/full
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