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Knockdown of the UL-16 binding protein 1 promotes osteoblast differentiation of human mesenchymal stem cells by activating the SMAD2/3 pathway

Abstract Osteoporosis is caused by the imbalance of osteoblasts and osteoclasts. The regulatory mechanisms of differentially expressed genes (DEGs) in pathogenesis of osteoporosis are of significant and needed to be further investigated. GSE100609 dataset downloaded from Gene Expression Omnibus (GEO...

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Principais autores: Zhen Lai, Mingming Li, Xiaodong Yang, Zhenjie Xian
פורמט: Artigo
שפה:Inglês
יצא לאור: BMC 2024-03-01
סדרה:BMC Musculoskeletal Disorders
נושאים:
Osteoporosis
Osteoblast differentiation
ULBP1
TNF-β
SMAD
גישה מקוונת:https://doi.org/10.1186/s12891-024-07341-0
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