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Pronecroptotic Therapy Using Ceramide Nanoliposomes Is Effective for Triple-Negative Breast Cancer Cells

Regulated necrosis, termed necroptosis, represents a potential therapeutic target for refractory cancer. Ceramide nanoliposomes (CNLs), considered potential chemotherapeutic agents, induce necroptosis by targeting the activating protein mixed lineage kinase domain-like protein (MLKL). In the present...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Yuki Ohya, Yuri Ogiso, Masaya Matsuda, Harumi Sakae, Kentaro Nishida, Yasuhiro Miki, Todd E. Fox, Mark Kester, Wataru Sakamoto, Takeshi Nabe, Kazuyuki Kitatani
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2024-02-01
Schriftenreihe:Cells
Schlagworte:
breast cancer
ceramide
ceramide nanoliposome
mixed-lineage kinase domain-like protein
necroptosis
triple-negative breast cancer
Online-Zugang:https://www.mdpi.com/2073-4409/13/5/405
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