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Long-Term Efficacy of Carboxymethyl-Chitosan in Advanced Knee Osteoarthritis: A Twelve-Month Follow-Up Study on Non-Responders to Hyaluronic Acid

<b>Background</b>: Knee osteoarthritis (OA) is a prevalent degenerative joint disease characterized by the degeneration of joint cartilage. Knee OA leads to pain, stiffness, swelling, and decreased mobility, significantly impacting the quality of life of affected people. Advanced-stage osteoarthriti...

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Main Authors: Nicola Manocchio, Carmelo Pirri, Concetta Ljoka, Andrea Sorbino, Nicolò Piacentini, Cristiano Monello, Giulia Vita, Calogero Foti
Format: Artigo
Language:Inglês
Published: MDPI AG 2025-01-01
Series:Biomedicines
Subjects:
knee osteoarthritis
intra-articular injections
carboxymethyl-chitosan
hyaluronic acid
quality of life
pain
Online Access:https://www.mdpi.com/2227-9059/13/2/270
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