Liver-specific expression of ANGPTL8 promotes Alzheimer’s disease progression through activating microglial pyroptosis
Abstract Introduction Liver dysfunction contributes to Alzheimer’s disease (AD) pathogenesis, and evidence suggests that the liver is involved in amyloid β (Aβ) clearance, and regulates Aβ deposition in the brain. However, the specific regulatory mechanism remains elusive. Objectives Angiopoietin-li...
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| Główni autorzy: | , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BMC
2025-07-01
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| Seria: | Journal of Neuroinflammation |
| Hasła przedmiotowe: | |
| Dostęp online: | https://doi.org/10.1186/s12974-025-03487-3 |
| Etykiety: |
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