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Gene-environment and gene-gene interactions between CHRNA3 rs1051730, XRCC1 rs25487, and ERCC1 rs735482 variants highly elevate the risk of lung cancer

Abstract Background Gene-gene and gene-environment interactions play an important role in cancer susceptibility. In this work, we studied the association of XRCC1 rs25487, ERCC1 rs735482, and CHRNA3 rs1051730 variants with lung cancer and assessed the modulatory effect of potential interaction betwe...

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Hlavní autoři: Nada Ezzeldin, Dalia El-Lebedy, Asmaa Mohammed
Médium: Artigo
Jazyk:Inglês
Vydáno: SpringerOpen 2019-11-01
Edice:Egyptian Journal of Medical Human Genetics
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On-line přístup:http://link.springer.com/article/10.1186/s43042-019-0034-1
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