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Dynamic capsule restructuring by the main pneumococcal autolysin LytA in response to the epithelium

Pneumococci produce a carbohydrate capsule that protects them against components of the host immune system but sensitizes them to host antimicrobial peptides. Here, Kietzman et al.show that pneumococci respond to antimicrobial peptides by capsule shedding, which requires the main autolysin LytA.

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Autors principals: Colin C. Kietzman, Geli Gao, Beth Mann, Lance Myers, Elaine I. Tuomanen
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2016-02-01
Col·lecció:Nature Communications
Accés en línia:https://doi.org/10.1038/ncomms10859
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