Identifying requirements for RSK2 specific inhibitors
Identifying isoform-specific inhibitors for closely related kinase family members remains a substantial challenge. The necessity for achieving this specificity is exemplified by the RSK family, downstream effectors of ERK1/2, which have divergent physiological effects. The natural product, SL0101, a...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis Group
2021-01-01
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| Edice: | Journal of Enzyme Inhibition and Medicinal Chemistry |
| Témata: | |
| On-line přístup: | http://dx.doi.org/10.1080/14756366.2021.1957862 |
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