The Use of Primary Spiral Ganglion Cells in Studying Glutamate Receptor Function and Excitotoxicity in the Cochlea

Sensorineural hearing loss (SNHL) can result from genetic mutations, excessive noise exposure, ototoxic drugs, and aging. Glutamate excitotoxicity is one of the underlying mechanisms of SNHL. However, the specific roles of different glutamate receptor subtypes in normal signaling and excitotoxic dam...

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Autores principales:	Eugenue V. Polikarpov, Elena A. Smolyarchuk, Andrey P. Fisenko, Zanda V. Bakaeva
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2026-04-01
Colección:	Cells
Materias:	spiral ganglion neurons spiral ganglion cells glutamate excitotoxicity primary cell culture sensorineural hearing loss neurotransmission
Acceso en línea:	https://www.mdpi.com/2073-4409/15/9/777
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