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Oligoprogression of Solid Tumors on Immune Checkpoint Inhibitors: The Impact of Local Ablative Radiation Therapy

The breakthrough of a limited number of clones while on immune checkpoint inhibitors (ICIs), known as oligoprogression, has been previously described. The benefit of ablative radiation therapy (RT) directed at these clones, as opposed to changing systemic therapy, is unclear. We analyzed 30 patients...

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Principais autores: Kunal K. Sindhu, Anthony D. Nehlsen, Eric J. Lehrer, Jared P. Rowley, Richard G. Stock, Matthew D. Galsky, Michael Buckstein
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-10-01
Serier:Biomedicines
Fag:
immunotherapy
oligoprogression
radiation therapy
Online adgang:https://www.mdpi.com/2227-9059/10/10/2481
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