Biotransformation of Maclekarpine E in Rats: CYP2C19-Mediated Metabolism, Fecal Enrichment, and Network Pharmacology-Based Anti-Ulcerative Colitis Prediction

Maclekarpine E is a minor alkaloid from <i>Macleaya</i> species with reported in vitro anti-inflammatory activity, but its in vivo metabolism remains unexplored. This study investigated the metabolic fate of maclekarpine E in rats and evaluated the potential pharmacological relevance of its metaboli...

Повний опис

Бібліографічні деталі

Автори:	Yingxue Yang, Lin Wang, Jiaojiao Xue, Zhen Dong, Pi Cheng
Формат:	Artigo
Мова:	Inglês
Опубліковано:	MDPI AG 2026-03-01
Серія:	Current Issues in Molecular Biology
Предмети:	maclekarpine E metabolite identification CYP2C19 ABCG2 network pharmacology
Онлайн доступ:	https://www.mdpi.com/1467-3045/48/3/335
Теги:	Додати тег Немає тегів, Будьте першим, хто поставить тег для цього запису!