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Nonstructural 5A Protein of Hepatitis C Virus Interferes with Toll-Like Receptor Signaling and Suppresses the Interferon Response in Mouse Liver.

The hepatitis C virus nonstructural protein NS5A is involved in resistance to the host immune response, as well as the viral lifecycle such as replication and maturation. Here, we established transgenic mice expressing NS5A protein in the liver and examined innate immune responses against lipopolysa...

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Збережено в:
Бібліографічні деталі
Автори: Takeya Tsutsumi, Kazuya Okushin, Kenichiro Enooku, Hidetaka Fujinaga, Kyoji Moriya, Hiroshi Yotsuyanagi, Hideki Aizaki, Tetsuro Suzuki, Yoshiharu Matsuura, Kazuhiko Koike
Формат: Artigo
Мова:Inglês
Опубліковано: Public Library of Science (PLoS) 2017-01-01
Серія:PLoS ONE
Онлайн доступ:https://doi.org/10.1371/journal.pone.0170461
Теги: Додати тег
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