Intracellular distribution of bis-allylic deuterated linoleic acid into the lipidome of human keratinocytes

Polyunsaturated fatty acids (PUFA) are particularly susceptible to free radical-induced lipid peroxidation (LPO). Specific deuteration at bis-allylic positions of PUFA (D-PUFA) has been recently proposed as a way to inhibit the LPO. Here, a high mass resolution untargeted lipidomic analysis protocol...

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Bibliografiske detaljer

Principais autores:	Rosangela S. Santos, Márcia S.F. Franco, Felipe G. Ravagnani, Adriano B. Chaves-Filho, Sayuri Miyamoto, Mauricio S. Baptista, Mikhail S. Shchepinov, Marcos Y. Yoshinaga
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2023-12-01
Serier:	Redox Biochemistry and Chemistry
Fag:	D-PUFA Deuterated linoleic acid Mass spectrometry Fatty acid incorporation
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2773176623000044
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