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Characterization of genetics in patients with mucosal melanoma treated with immune checkpoint blockade

Abstract Mucosal melanoma is a rare form of melanoma which arises from melanocytes in the mucosal membranes and can be effectively treated with immune checkpoint blockade (ICB). However, response rates in mucosal melanoma are lower than those observed for cutaneous melanomas. Targeted sequencing of...

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Autori principali: Elizabeth I. Buchbinder, Jason L. Weirather, Michael Manos, Brian J. Quattrochi, Lynette M. Sholl, Ryan C. Brennick, Peter Bowling, Nancy Bailey, Lisa Magarace, Patrick A. Ott, Rizwan Haq, Benjamin Izar, Anita Giobbie‐Hurder, F. Stephen Hodi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley 2021-04-01
Serie:Cancer Medicine
Soggetti:
genetics
immune checkpoint blockade
immunotherapy
KIT mutation
mucosal melanoma
Accesso online:https://doi.org/10.1002/cam4.3789
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